Ribociclib also known as Kisqali is used in the treatment of breast cancer. It is a kinase inhibitor that inhibits the function of CDK4 and 6 (cyclin-dependent kinase). This blocks the cell division process in the cells. As a result, it stops the uncontrollable growth and metastasis of cancerous cells of breast cancer. Ribociclib tablet is taken orally for 21 days in a 28-day cycle of treatment.

Survival rate of Ribociclib                              

Ribociclib 600mg tablet is a part of targeted therapy. It is often given in combination with fulvestrant and letrozole to improve the success rate of the treatment. Studies have shown that using ribociclib in combination with letrozole increased the life expectancy to 64 months whereas, it was 51 months with just letrozole. Using ribociclib along with hormone therapy improves the survival rates and also reduces the risk of relapsing.

Side effects

• Breathing complications – shortness of breath, chills, cough, wheezing.
• Bleeding- occurs due to decreased platelet count. The appearance of blood in urine, stool, excessive nosebleeds, and gum bleeding.
• Weakened immune system – increased risks of infections, fever, and urinary tract infections
• Liver complications - dark urine, yellowing of skin and eyes are a few of the initial symptoms of liver disorder
• Loss of appetite, nausea, and fatigue are a few of the common symptoms
• Low magnesium, calcium, and potassium levels - can lead to muscle cramps, lightheadedness, irregular heart rate, and numbness in arms and feet.

Precautions

• Some of the components of Ribociclib 600mg tablet can cause an allergic response. Redness, rashes, swelling, and hives are the common signs of allergic reactions. Hence, it is advisable to read the ingredient list and consult the doctor in case of an issue.
• The medication can interact with vitamin supplements, antibacterial and antifungal drugs. It can interact with them and further block their mechanism of action.
• Ribociclib can harm the fetus. Hence, pregnancy should be avoided during the treatment and till 3 weeks after the final dose.
• Informing the doctor in case of prior heart issues and irregular levels of calcium and phosphorous.

Conclusion
Ribociclib tablets are an efficient drug for the treatment of advanced breast cancer. They are not just safe to use but also improve the survival rate when used in combinations. Magicine Pharma can be used to purchase this medicine.