One medication that helps men with long-term erectile dysfunction is Tadalista 60. Those who experience anxiety, panic attacks, depression, or impotence can benefit greatly from this medication. Tadalafil, a deadly ingredient in this medication, gives men strong erections during sexual activity. You can take this medication either way—before or after food. Before using the medication, one should see a doctor if excessive use poses risks. Drinks that are fatty or cold should be avoided right after taking this medication because they will decrease its effectiveness. This medication takes three to four hours to take effect.